Leeds Archives - Ocular Melanoma UK

The HistoSonics System for Treatment of Primary and Metastatic Liver Tumors Using Histotripsy

January 23, 2025

This is a single-arm, non-randomized prospective trial designed to assess the effectiveness and safety of the HistoSonics System, a novel treatment for primary or metastatic liver tumors. The trial aims to evaluate how well the system works and its safety profile in targeting liver tumors.

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First in Human Study of T3P-Y058-739 (T3P)

This is the first trial in humans to test T3P-Y058-739, a genetically modified and weakened strain of the bacterium Yersinia enterocolitica. The study aims to find the right dose, test its safety, and see how well it works in people with advanced solid tumours.